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INMB

INmune Bio

$7.70 /

-0.74 (-8.77%)

07:39
11/09/20
11/09
07:39
11/09/20
07:39

INmune Bio doses first patient in Phase 2 trial of Quellor

INmune Bio announced that the first patient has been dosed in its Phase 2 clinical trial evaluating Quellor for the treatment of pulmonary complications from COVID-19. Quellor is a selective soluble Tumor Necrosis Factor inhibitor designed to potentially prevent the progression of immune mediated pulmonary complications resulting from SARS-CoV-2 viral infection. The dosing of the first patient took place at UofL Health - Jewish Hospital, Louisville, KY. As the largest academic health system in Kentucky, UofL Health is committed to increasing regional access to leading edge treatments and therapies. The double-blind, randomized, placebo-controlled Phase 2 clinical trial will enroll 366 COVID-19 high risk patients in two equal sized cohorts: standard of care, which may include remdesivir, and SOC plus Quellor given as a 1mg/kg subcutaneous injection on admission to the hospital. A second dose of Quellor may be given a week later if the patient remains hospitalized. High risk patients include the elderly, patients with diabetes, cardiovascular disease, obesity, African American or Hispanic ethnicity. The primary study endpoint is the need for mechanical ventilation during the 28 days following admission to the hospital, including CPAP, BiPAP or intubation. Secondary endpoints include transfer to the ICU, new onset neurologic, cardiovascular or thromboembolic disease, development of renal failure or death. The first 100 patients randomized into the study will provide proof-of-concept and inform a "go/no go" decision by the Data Safety Monitoring Board. If the DSMB recommends that the trial continue, the remaining 266 patients will be enrolled.

  • 16

    Jul

INMB INmune Bio
$7.70 /

-0.74 (-8.77%)

09/01/20 BTIG
INmune Bio initiated with a Buy at BTIG
07/14/20 Roth Capital
INmune Bio price target raised to $26 from $13 at Roth Capital
03/12/20 H.C. Wainwright
INmune Bio price target lowered to $8 from $11 at H.C. Wainwright
03/11/20 Roth Capital
INmune makes progress in all programs, novel COVID-19 approach,says Roth Capital

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Conference/Events
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Conference/Events
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Conference/Events
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Recommendations
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  • 18
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Technical Analysis
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Technical Analysis
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Syndicate
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