2020-12-01 06:22:58 BDSX Biodesix
12/01/20 12/0106:22 12/01/2006:22 | Biodesix publishes extended analysis of Nodify XL2 lung nodule testBiodesix announced publication of an analysis of the company's Nodify XL2 lung nodule test. The test supports clinical decision-making for suspicious nodules by more accurately identifying patients with a very low risk of malignancy and shifting those patients into surveillance, thereby minimizing invasive procedures on those with benign nodules. In previously published findings from the Pulmonary Nodule Plasma Proteomic Classified Trial, the Nodify XL2 test was shown to accurately identify patients with lung nodules who have a pre-test risk of malignancy less than 50% as "likely benign." After one year of follow-up, the test demonstrated a sensitivity of 97%, specificity of 44%, and negative predictive value of 98%, which is more accurate than other commonly used lung nodule risk assessment calculators. The new paper, published in the American College of Chest Physicians Journal, presents findings that all nodules in the study group that were established as benign after one year remained benign after two years of follow-up. This data confirms the performance of the Nodify XL2 test over the guideline-recommended two-year surveillance period to radiologically confirm a benign diagnosis. Additionally, a new analysis suggests that the classifier performs similarly regardless of the whether the nodule of concern was solitary or there were other nodules present. |
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